DIABETROL 5+500MG

Diabetrol 5+500mg

Diabetrol 5+500mg is a combination medication primarily used for managing type 2 diabetes mellitus. It combines glibenclamide (5mg), a sulfonylurea that stimulates insulin production, with metformin (500mg), a biguanide that improves insulin sensitivity and reduces hepatic glucose production.

Together, they help lower blood sugar levels effectively. This dual action targets both insulin secretion and glucose utilization, making it a powerful choice for diabetic patients who cannot control their blood sugar with lifestyle changes alone. Diabetrol should be used with caution, especially in patients with renal or hepatic impairment.

Uses 

• Type 2 Diabetes Management – Combines glibenclamide and metformin to effectively control blood sugar levels in people with type 2 diabetes.
• Insulin Production Stimulation – Glibenclamide promotes insulin release from the pancreas.
• Improves Insulin Sensitivity – Metformin enhances the body’s response to insulin, reducing insulin resistance.
• Reduces Hepatic Glucose Production – Metformin decreases excess glucose production by the liver.
• Combination Therapy – Used when diet and exercise alone do not sufficiently manage blood sugar levels.
• Long-Term Diabetes Control – Helps in the prevention of diabetes complications such as nerve or kidney damage.

How to use it ?

Take Diabetrol 5+500mg as prescribed by your doctor, typically one tablet once or twice daily with meals to minimize side effects. Swallow the tablet whole with water—do not crush or chew it. Consistency is key, so take it at the same time each day.

Monitor blood sugar regularly to ensure effective control. If you miss a dose, take it as soon as you remember, but don’t double doses. Avoid alcohol as it may interfere with blood sugar control.

How Diabetrol 5+500mg Works ?

Diabetrol 5+500mg combines glibenclamide (5mg) and metformin (500mg), each targeting different mechanisms to control blood sugar levels in type 2 diabetes.

• Glibenclamide (5mg) – A sulfonylurea that stimulates insulin production from the pancreas, helping lower blood sugar by increasing insulin levels in the body.
• Metformin (500mg) – A biguanide that improves insulin sensitivity, reduces glucose production in the liver, and increases glucose uptake in muscles, helping cells utilize sugar more effectively.

Dosage

The typical starting dose of Diabetrol 5+500mg is 1 tablet once or twice daily, usually taken with meals. Your doctor may adjust the dosage based on your blood sugar levels, but the maximum daily dose is typically 2 tablets (10mg glibenclamide and 1,000mg metformin).

If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not double doses.

Benefits of Diabetrol 5+500mg:

• Effective Blood Sugar Control – Combines glibenclamide and metformin to provide dual-action in lowering blood glucose levels.
• Improves Insulin Sensitivity – Metformin enhances the body’s response to insulin, reducing insulin resistance.
• Stimulates Insulin Production – Glibenclamide helps the pancreas release more insulin, aiding in blood sugar management.
• Reduces Liver Glucose Production – Metformin decreases excessive glucose production in the liver.
• Prevents Diabetes Complications – Helps reduce the risk of long-term complications like heart disease and nerve damage.
• Convenient Combination – One medication for both insulin secretion and glucose utilization, simplifying diabetes management.

Side Effects 

• Hypoglycemia (Low Blood Sugar) – Symptoms include shakiness, sweating, dizziness, confusion, and weakness.
• Gastrointestinal Issues – Common side effects like nausea, vomiting, bloating, and diarrhea may occur, especially with metformin.
• Headache & Dizziness – Can affect concentration and balance.
• Weight Gain – Some patients may experience slight weight gain due to glibenclamide.
• Liver Problems – Rare cases of liver dysfunction or jaundice (yellowing of the skin/eyes).
• Allergic Reactions – Rashes, itching, or swelling, especially in sensitive individuals.

Precautions 

• Avoid Alcohol – Alcohol increases the risk of hypoglycemia and can interfere with diabetes control.
• Monitor Blood Sugar Regularly – Regularly check your blood sugar levels to prevent low or high blood sugar episodes.
• Kidney & Liver Impairment – Use with caution in people with kidney or liver problems, as metformin can affect these organs.
• Not for Type 1 Diabetes – Diabetrol is not effective for type 1 diabetes, as it requires functioning insulin production.
• Pregnancy & Breastfeeding – Consult your doctor before using during pregnancy or breastfeeding, as alternatives may be safer.
• Monitor for Hypoglycemia – Be mindful of symptoms like sweating, shaking, and dizziness, especially if meals are skipped or physical activity is increased.
• Discontinue if Allergic Reactions Occur – Stop use and seek medical attention if you notice rash, swelling, or difficulty breathing.

Frequently Asked Questions 

What is Diabetrol 5+500mg used for?

Diabetrol 5+500mg is used to manage type 2 diabetes by combining glibenclamide, which stimulates insulin release, and metformin, which improves insulin sensitivity and reduces liver glucose production.

How should I take Diabetrol 5+500mg?

Take 1 tablet once or twice daily, with meals, as prescribed by your doctor. Always swallow whole, without chewing or breaking the tablet.

Can Diabetrol 5+500mg cause low blood sugar (hypoglycemia)?

Yes, hypoglycemia is a possible side effect, especially if meals are skipped, exercise increases, or doses are missed. Symptoms include shaking, sweating, or dizziness.

How long does it take for Diabetrol to work?

You may begin to see a reduction in blood sugar within a few days, but full effects may take 1-2 weeks to be noticed.

Can I take Diabetrol 5+500mg with other medications?

It can be combined with other antidiabetic drugs, but consult your doctor for potential adjustments and interactions, especially with insulin or other oral medications.

Is Diabetrol safe for pregnant or breastfeeding women?

It is generally not recommended during pregnancy or breastfeeding. Speak to your doctor for safer alternatives.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. Do not double doses to make up for the missed one. If it’s near the next dose, skip the missed one.

Can I drink alcohol while using Diabetrol 5+500mg?

Avoid alcohol as it can increase the risk of hypoglycemia and interfere with blood sugar control.

What are the common side effects of Diabetrol 5+500mg?

Common side effects include nausea, diarrhea, weight gain, dizziness, and low blood sugar.

 How should I store Diabetrol 5+500mg?

Store the medication in a cool, dry place at room temperature, away from direct sunlight and moisture.

Conclusion

Diabetrol 5+500mg is an effective medication for managing type 2 diabetes, combining glibenclamide to stimulate insulin release and metformin to improve insulin sensitivity and reduce liver glucose production.

It helps control blood sugar levels when combined with a healthy lifestyle. However, it’s important to follow your doctor’s guidance, monitor blood sugar, and be cautious of side effects like hypoglycemia. Always take it with meals for optimal results.